Extramedullary plasmacytoma is a rare disease, which arises most commonly in the head and neck. We have recently treated a 34-year-old male with multiple occurences of extramedullary plasmacytoma originating in the epipharynx, posterior pharyngeal wall, tonsils and larynx. Histopathologic studies revealed to be a IgG-κ producing plasmacytoma.
It has been reported that radiation therapy is the most effective treatment for extramedullary plasmacytoma, but surgical therapy was useful in this radio-resistant case.