PXD009798

PXD009798 is an original dataset announced via ProteomeXchange.

Title	Specialisation events of fungal metacommunities exposed to a persistent organic pollutant are suggestive of augmented pathogenic potential
Description	The impacts of man-made chemicals, in particular of persistent organic pollutants, are multifactorial as they may affect the integrity of ecosystems, alter biodiversity and hinder the health of most organisms. We have demonstrated that the belowground mycobiota of forest soils acts as a buffer against the pollution provoked by the biocide pentachlorophenol. However the trade-offs of the mitigation of the pollutant remain cryptic. To address this question we scrutinised the key changing aspects of a metacommunity of fungi when confronted (or not) with the biocide, comprising taxonomic and functional levels, as well as the identification of the major pollutant degraders within the metacommunity. Exposure to the biocide led to alterations in the metacommunity composition and functioning, many of which were not fully alleviated when most of the biocide was degraded, especially the dysregulation of the carbon and nitrogen metabolisms. The last is possibly linked to the higher pathogenic potential of the metacommunity after exposure to the biocide, supported by the secretion of proteins related to pathogenicity and reduced susceptibility to a standard fungicide. Our findings provide additional evidence for the silent risks of environmental pollution, particularly as it may favour the development of pathogenic trade-offs in fungi, which may impose serious threats to animals and plant hosts.
HostingRepository	PRIDE
AnnounceDate	2018-12-04
AnnouncementXML	Submission_2018-12-04_01:41:22.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD009798
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Céline LECLERCQ
SpeciesList	scientific name: environmental samples ; NCBI TaxID: 57731;
ModificationList	Acetyl; Carbamidomethyl; Oxidation; Gln->pyro-Glu
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2018-05-16 05:49:52	ID requested
1	2018-11-28 02:47:08	announced
⏵ 2	2018-12-04 01:41:24	announced	Updated project metadata.

Martins C, Varela A, Leclercq CC, N, ú, ñ, ez O, V, ě, trovsk, ý T, Renaut J, Baldrian P, Silva Pereira C, Specialisation events of fungal metacommunities exposed to a persistent organic pollutant are suggestive of augmented pathogenic potential. Microbiome, 6(1):208(2018) [pubmed]

curator keyword: Biomedical

submitter keyword: metacommunity, biocide, pathogenic, PCP, secreted proteins, carbon and nitrogen metabolisms, LC-MS

Jenny Renaut
contact affiliation	LIST-ERIN-ERTP
contact email	Jenny.renaut@list.lu
lab head
Céline LECLERCQ
contact affiliation	LIST-ERIN-ERTP-IBP
contact email	celine.leclercq@list.lu
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD009798
     1. Label: PRIDE project
     2. Name: Specialisation events of fungal metacommunities exposed to a persistent organic pollutant are suggestive of augmented pathogenic potential