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Heterotypic transcriptional condensates formed by prion-like paralogous proteins canalize flowering transition in tomato

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posted on 2022-03-04, 12:50 authored by Xiaozhen HuangXiaozhen Huang, Nan Xiao, Yue Xie, Lingli Tang, Yueqin Zhang, Yuan Yu, Yiting Li, Cao Xu

Our study reveals a novel genetic canalization mechanism enabled by heterotypic transcriptional condensates formed by paralogous protein interactions and phase separation, uncovering the molecular link between gene duplication caused IDR variation and robust transcriptional control of stem cell fate transition.

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