Regulation of Enzyme Activity through Interactions with Nanoparticles
Abstract
:1. Introduction
2. Effects of Mixed Monolayer Protected Nano Clusters (MMPCs)
3. Influence of the Size of NP on the Activity of Adsorbed Enzymes
4. Conformational Changes as a Result of NP/Protein Binding
5. Regulation of Enzyme Function by Surface-Modified NPs
6. Fine Tuning of NP/Protein Interactions
7. Conclusions
Acknowledgments
References
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Kib (nM) | |||
---|---|---|---|
Compound | hCA I | hCA II | hCA IX |
AZA | 250 ± 12 | 12 ± 1 | 25 ± 1 |
8 | 214 ± 9 | 230 ± 10 | 41 ± 2 |
GNP-8 | 581 ± 18 (128) | 451 ± 21 (116) | 32 ± 2 (2.4) |
9 | >50,000 | >50,000 | >50,000 |
GNP-9 | 28,550 | 30,400 | 31,050 |
Au | 32,000 | 31,600 | 29,560 |
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Wu, Z.; Zhang, B.; Yan, B. Regulation of Enzyme Activity through Interactions with Nanoparticles. Int. J. Mol. Sci. 2009, 10, 4198-4209. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms10104198
Wu Z, Zhang B, Yan B. Regulation of Enzyme Activity through Interactions with Nanoparticles. International Journal of Molecular Sciences. 2009; 10(10):4198-4209. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms10104198
Chicago/Turabian StyleWu, Zhaochun, Bin Zhang, and Bing Yan. 2009. "Regulation of Enzyme Activity through Interactions with Nanoparticles" International Journal of Molecular Sciences 10, no. 10: 4198-4209. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms10104198